Phytochemical and Pharmacological potential of Flemingia Roxb. ex W.T.Aiton (Fabaceae)

Kavita Gahlot, V. K. Lal, S. Jha

Abstract


The Flemingia genus is an important source of medicinal natural products, particularly Flavonoids and steroids. The collected information is an attempt to cover the more recent developments in the ethnobotany, pharmacology and phytochemistry of this genus. The review includes 39 references on the genus Flemingia, and comprises ethnopharmacology, morphology, phytoconstituents, pharmacological reports, clinical study and adverse effects of the prominent species of Flemingia. A few species of this genus have medicinal value, among these, F.strobilifera ,F.macrophylla, F.chappar (Fabaceae) have been traditionally used in the treatment of epilepsy, insomnia, ulcer, pain ,swelling. Despite a long tradition of use of some species, the genus has not been explored properly. In the concluding part, the future scope of Flemingia species has been emphasized with a view to establish their multifarious biological activities and mode of action. The information summarized here is intended to serve as a reference tool to practitioners in the fields of ethnopharmacology and natural products chemistry.

Key words: Flemingia strobilifera, F. macrophylla, F.chappar, Fabaceae, Flavonoids


References


Badwaik H, Singh MK, Thakur D, Kumar T Giri, Tripathi DK.The Botany ,Chemistry,Pharmacological and Therapeutic application of Oxalis corniculata Linn. International Journal of Phytomedicine.2011, (3) 1-8.

Anonymous, The Wealth of India, Raw Materials, Publication and Information Directorate, CSSIR, New Delhi, 1993, vol.4th pp.45-48.

http://en.wikipedia.org/wiki/Flemingia.

Wei Yuetsung. The classification and distribution

of the genus flemingia roxb.ex ait.in china.Guihaia. 1991, 03.

Sa Ren, Michael G. Gilbert. . FLEMINGIA Roxburgh ex W. T. Aiton, Hort. Kew., ed. 2, 4: 349. 1812, nom. cons., not Roxburgh ex Rottler. Flora of China .2010, 10, 232–237.

Oudhia, P. Medicinal herbs of chhattisgarh, India having legumes Traditional uses, VIII.Manjholi Galfulli (Flemingia chappar). Botanical.com. 2003.

http://www.science20.com/humboldt_fellow_and_science/blogspot."Plants used in folk medicine in India believed to have medicinal potential by users of folk medicine in India".

http://uvp.blogspot.com/2006.05/flemingia.html UBINVOLUNTEERS.

Kirtikar, K.R. and Basu, B.D., Indian Medicinal Plants, 1993, Vol.1, pp.814-815.

http://www.stuartxchange.org/panapanarahan/payang-payang.html.

http://toptropicals.com/cgi-bin/garden_catalog/cat.cgi.

http://www.flowersofindia.in/catalog/slides/Wild%20Hops.html.

Adityachaudhary N, Ghosh D, ChoudharyA, Kirtaniya CL. flemichapparin-A a new chromenochalcone isolated from Flemingia chappar. Journal of the Indian chemical society.1973; 59 (5):363-4.

Adityachaudhary N, Gupta PK. New pterocarpan and coumestan in the roots of Flemingia chappar. Phytochemistry.1973;12 (2):425-8.

Dhar DN, Singh RK, Munjal RC. Chemical examination of Flemingia chappar. Root constituents. Monatsh.Chem.1971;102(6):1777-81.

Rao CP, Vemuri VSS, Rao KVJ. Chemical examinations of roots of Flemingia stricta Roxb. (Leguminosae). Indian journal of chemistry.1982; 21B (2): 167-9.

Sivarambabu S, Rao JM, Rao KVJ.New flavanones from the roots of Flemingia stricta roxb. Indian journal of chemistry. 1979;17B(1): 85-7

Rastogi PR, Mehrotra BM. compendium of Indian medicinal plants vol. 2 CDRI , Lucknow,1991; P323.

Subramanyam K, Rao JM, Vemuri VSS, Babu SS, Roy CP, Rao KVJ, Merlini L. New chalcones from the leaves of flemingia stricta Roxb., (Leguminosae)Indian journal of Chemistry. 1982;21B (9) :895-7.

Rao JM, Subrahmanyam K, Jagannadha KV, Ramaih TS. New chalcones from the leaves of Flemingia stricta Roxb.(Leguminosae) . Indian journal of chemistry. 1976;14B (5): 339-42.

Nageshwara K, Srimannarayana G. Fleminone a flavanone from the stems of Flemingia macrophylla, Journal of Phytochemistry. 1983; 22(10) : 2287-2290.

Nageshwara K, Srimannarayana G. Flemiphyllin an isoflavone from stems of Flemingia macrophylla, Journal of Phytochemistry 1984; 23(4): 927-929.

Saxena VK, Nigam SS, Singh RB. Glycosidic principles from the leaves of Flemingia strobilifera. Planta Medica. 1976; 29(91):94-7.

Bhatt S. Chalcones and some other constituents of Flemingia strobilifera Indian journal of Chemistry. 1975;13(100):1105-08.

Madan S, Singh GN, Kumar Y. A New Flavanone from Flemingia strobilifera (Linn) R.Br. and its Antimicrobial Activity. Trop J Pharm Res. 2008 Mar; 7 (1): 921-27.

Madan S, Singh GN, Kanchan K. Isoflavonoids from Flemingia Strobilifera (L) R.Br. roots. Acta Poloniae Pharmaceutica-Drug research. 2009 66(3): 297-303.

Supplements of Indian herbs vol.1.

Rao HSP, Reddy KS. Isoflavones from Flemingia vestita Fitoterapia. 1991;62(5) :458.

Compendium of Indian medicinal plants, and phytochemistry. 1973.

M Chen, S Q Luo, J H Chen. Studies on the chemical constituents of Flemingia philippinensisby Acta pharmaceutica Sinica .1991; 26( 1): 42-48

Glossary of Indian Medicinal plants with active principles part -1(A-K).1965-1981.

Madan S, Singh GN, Kumar Y, Kanchan K. Phytochemical analysis and free-radical scavenging activity of Flemingia strobilifera (Linn) R. Br. Research Journal of Pharmaceutical,Biological and Chemical Sciences.2010;1 (4): 183.

Anil Kumar KV, Babul D, Rama T. Evaluation of anti-ulcerogenic properties from the root of Flemingia strobilifera. Journal of Basic and Clinical Pharmacy .2011;002 (001).

Hui-Ya Ho, Jin-Bin Wu , Wen-Chuan Lin. Flemingia macrophylla Extract Ameliorates Experimental Osteoporosis in Ovariectomized Rats Evidence-based Complementary and Alternative Medicine. 2009; 7(4).

Hsieh PC, Ho YL, Huang GJ, Huang MH, Chiang YC, Huang SS, Hou WC, Chang YS. Hepatoprotective effect of the aqueous extract of Flemingia macrophylla on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities. Am J Chin Med, 2011; 39(2):349-65.

Shiao YJ.,Wang CN, Wang WY,Lin YZ., Neuroprotective flavonoids from F.macrophylla. J. Of Planta Medica.2006; 7(9): 835-840.

Das B, Tandon V, Saha N. Anthelmintic efficacy of Flemingia vestita (Fabaceae): alterations in glucose metabolism of the cestode, Raillietina echinobothrida. Parasitology International .2004; 53(4): 345-350.

Tandon V, Das B, Saha N. Anthelmintic efficacy of Flemingia vestita (Fabaceae): Effect of genistein on glycogen metabolism in the cestode, Raillietina echinobothrida. Parasitol Int. 2003 Jun; 52(2):179-83

Kar PK, Tandon V, Saha N. Anthelmintic efficacy of Flemingia vestita: genistein-induced effect on the activity of nitric oxide synthase and nitric oxide in the trematode parasite, Fasciolopsis buski. Parasitol Int. 2002 Sep; 51(3):249-57.


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