PHARMACOGNOSTIC STUDIES AND ANTIINFLAMMATORY ACTIVITIES OF CLERODENDRUM VOLUBILE P Beauv LEAF

ADEDIWURA JAIYESIMI, YEWANDE ADEKOYA

Abstract


Clerodendrum volubile P Beauv (Verbenaceae) is a climbing shrub used traditionally in the treatment of swelling, gout and venereal diseases.  In this study, the microscopic, macroscopic, phytochemical analysis and anti-inflammatory activities were investigated using standard procedures. 

The results revealed the presence of alkaloids, flavonoids, saponins, anthraquinone and cardiac glycoside while the methanol extract, petroleum ether and ethyl acetate fractions exhibited significant (p<0.05) anti-inflammatory activities when compared to the effect of the reference drug Diclofenac sodium.


Keywords


anti-inflammatory, Clerodendrum volubile, macroscopy, microscopy, phytochemical screening

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